Scientists have used the principles that guide a mosquito's nocturnal flight to develop a quadcopter equipped with an elegant collision-avoidance sensory system. Their research, published in Science , demonstrates how the mosquito avoids obstacles in the dark by sensing changes in the airflows generated by its flapping wings. The international collaborative research group, which includes Dr. Simon Walker from the University of Leeds and was led by Professor Richard Bomphrey at the Royal Veterinary College (RVC), used the understanding of the sensory mechanism in the male Culex quinquefasciatus mosquito to develop a bio-inspired collision avoidance system for an autonomous quadcopter—which encodes aerodynamic information on the fly. The research also featured collaboration with Toshiyuki Nakata from Chiba University, PatrÃcio Simões and Ian Russell from the University of Brighton. Nocturnal mosquitoes navigate in the dark without crashing into surfaces. When they lan...
Although detailed mechanics of the immune response are beyond the scope of this site, it is useful, in the context of developing a custom antibody, to have an overview of how antibodies are produced by the immune system. When an organism’s immune system encounters a foreign molecule (typically a protein) for the first time, specialized cells such as macrophages and dendritic cells capture the molecule and begin breaking it down so that it can present these antigens to B cell lymphocytes. Once Antigen Presentation to the B cell lymphocytes has occurred, a process known as Somatic Hypermutation allows the B cell to begin coding for a new antibody that will contain a unique Antigen Binding Site in the variable region that is capable of binding specifically to an epitope from the antigen. Each B cell lymphocyte produces one unique antibody against one unique epitope. Once antibodies with sufficient specificity to the epitope can be encoded, the B ce...